8HOG
Crystal structure of Bcl-2 in complex with sonrotoclax
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Apoptosis regulator Bcl-2 | polymer | 162 | 18976.1 | 1 | Pfam (PF02180) Pfam (PF00452) UniProt (by SIFTS) (P10415) In PDB | Homo sapiens | |
| 2 | A | ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide | non-polymer | 890.1 | 1 | Chemie (98I) | |||
| 3 | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18976.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 890.1 | |
| All* | Total formula weight | 19866.2 |
