8HN4

Complex structure of HLA2402 with recognizing SARS-CoV-2 epitope QYIKWPWYI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class I antigen	polymer	308	35437.1	1	UniProt (F6IR24) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)
2	B (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C (E)	SARS-CoV-2 T-cell epitope QYIKWPWYI	polymer	9	1297.5	1	UniProt (by SIFTS) (P0DTC2)	Severe acute respiratory syndrome coronavirus 2

Sequence modifications

A: 25 - 300 (UniProt: F6IR24)

PDB	External Database	Details
Met 20	-	initiating methionine
Asn 21	-	expression tag
Ser 22	-	expression tag
Val 23	-	expression tag
Asp 24	-	expression tag
Gly 301	-	expression tag
Ser 302	-	expression tag
Gly 303	-	expression tag
Leu 304	-	expression tag
Asn 305	-	expression tag
Asp 306	-	expression tag
Ile 307	-	expression tag
Phe 308	-	expression tag
Glu 309	-	expression tag
Ala 310	-	expression tag
Gln 311	-	expression tag
Lys 312	-	expression tag
Ile 313	-	expression tag
Glu 314	-	expression tag
Trp 315	-	expression tag
His 316	-	expression tag
Ala 317	-	expression tag
Ala 318	-	expression tag
Ala 319	-	expression tag
Leu 320	-	expression tag
Glu 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48613.9
All*	Total formula weight	48613.9

*Water molecules are not included.