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8HLY

Crystal structure of SIRT3 in complex with H3K23la peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-3, mitochondrialpolymer28131253.01UniProt (Q9NTG7)
Pfam (PF02146)
Homo sapiens (human)hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3
2B
(B)
H3K23la peptidepolymer6618.71UniProt (by SIFTS) (P68431)Homo sapiens
3C, F, H
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
4D
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6G
(B)
(2S)-2-HYDROXYPROPANOIC ACIDnon-polymer90.11Chemie (2OP)
7I, J
(A, B)
waterwater18.0169Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight31871.7
Non-Polymers*Number of molecules6
Total formula weight493.8
All*Total formula weight32365.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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