8HK5
C5aR1-Gi-C5a protein complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | C5a anaphylatoxin chemotactic receptor 1 | polymer | 350 | 39372.4 | 1 | UniProt (P21730) Pfam (PF00001) | Homo sapiens (human) | |
| 2 | B (B) | Complement C5 | polymer | 74 | 8288.7 | 1 | UniProt (P01031) Pfam (PF01821) | Homo sapiens (human) | |
| 3 | C (C) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40313.9 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | |
| 4 | D (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P54311) Pfam (PF00400) | Rattus norvegicus (Norway rat) | |
| 5 | E (G) | Guanine nucleotide-binding protein subunit gamma | polymer | 67 | 7432.6 | 1 | UniProt (A0A6J0WY55) Pfam (PF00631) UniProt (by SIFTS) (P63212) | Bos taurus (cattle) | |
| 6 | F, G (A) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) |
Sequence modifications
C: 2 - 354 (UniProt: P63096)
D: 2 - 340 (UniProt: P54311)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | cloning artifact |
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Leu -1 | - | cloning artifact |
| Leu 0 | - | cloning artifact |
| Gln 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 133323.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 512.8 | |
| All* | Total formula weight | 133835.8 |
