8HJE
Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ubiquitin carboxyl-terminal hydrolase 28 | polymer | 380 | 44432.5 | 1 | UniProt (Q96RU2) Pfam (PF00443) In PDB | Homo sapiens (human) | Deubiquitinating enzyme 28,Ubiquitin thioesterase 28,Ubiquitin-specific-processing protease 28 |
2 | A | 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide | non-polymer | 421.3 | 1 | Chemie (VIS) |
Sequence modifications
A: 150 - 399 (UniProt: Q96RU2)
A: 580 - 703 (UniProt: Q96RU2)
A: 580 - 703 (UniProt: Q96RU2)
PDB | External Database | Details |
---|---|---|
Gly 400 | - | linker |
Ser 575 | - | linker |
Gly 576 | - | linker |
Ser 577 | - | linker |
Gly 578 | - | linker |
Ser 579 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44432.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 421.3 | |
All* | Total formula weight | 44853.8 |