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8HIT

Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
JS007-VHpolymer11813101.41Mus musculus
2B
(B)
JS007-VLpolymer10711700.01Mus musculus
3C
(C)
Cytotoxic T-lymphocyte protein 4polymer12012869.71UniProt (P16410)
Pfam (PF07686)
Homo sapiens (human)Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37671.1
All*Total formula weight37671.1
*Water molecules are not included.

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PDB entries from 2024-11-13

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