8HIN
Structure of human SGLT2-MAP17 complex with Phlorizin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/glucose cotransporter 2 | polymer | 676 | 73247.7 | 1 | UniProt (P31639) Pfam (PF00474) | Homo sapiens (human) | Na(+)/glucose cotransporter 2,Low affinity sodium-glucose cotransporter,Solute carrier family 5 member 2 |
| 2 | B (B) | PDZK1-interacting protein 1 | polymer | 114 | 12235.0 | 1 | UniProt (Q13113) Pfam (PF15807) | Homo sapiens (human) | 17 kDa membrane-associated protein |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one | non-polymer | 436.4 | 1 | Chemie (LN9) PubChem (16758124) PubChem (17759822) PubChem (6072) PubChem (25766924) PubChem (25791508) PubChem (25791509) PubChem (44655905) PubChem (45040243) PubChem (45933907) PubChem (25791507) PubChem (40481259) PubChem (73265329) PubChem (60020392) PubChem (70687204) PubChem (4789) PubChem (7059601) PubChem (6604686) PubChem (99721165) PubChem (101614383) PubChem (7059602) PubChem (7059603) PubChem (122524631) PubChem (124427661) PubChem (142039241) PubChem (12358713) PubChem (171395314) PubChem (143932286) PubChem (144780110) PubChem (154746925) PubChem (163014468) PubChem (163014469) PubChem (163285253) |
Sequence modifications
A: 1 - 672 (UniProt: P31639)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85482.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 657.6 | |
| All* | Total formula weight | 86140.3 |
