8HHP
Crystal structure of PPARg-LBD complexed with three partial agonists, one nTZDpa and two LT175
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31449.5 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | |
| 2 | B (A) | 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID | non-polymer | 428.3 | 1 | Chemie (NZA) | |||
| 3 | C, D (A) | (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid | non-polymer | 318.4 | 2 | Chemie (LRG) | |||
| 4 | E (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 204 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
| Ala 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31449.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1065.1 | |
| All* | Total formula weight | 32514.6 |
