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8HFG

Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium-dependent noradrenaline transporterpolymer61769386.51UniProt (P23975)
Pfam (PF00209)
Homo sapiens (human)Norepinephrine transporter,NET,Solute carrier family 6 member 2
2B, C
(A)
L-DOPAMINEnon-polymer153.22Chemie (LDP)
3D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4E
(A)
waterwater18.05Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69386.5
Non-Polymers*Number of molecules3
Total formula weight341.8
All*Total formula weight69728.4
*Water molecules are not included.

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PDB entries from 2024-12-18

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