8H78
Crystal structure of human MMP-2 catalytic domain in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Matrix metalloproteinase-2 | polymer | 168 | 18809.9 | 2 | Pfam (PF00413) UniProt (by SIFTS) (P08253) | Homo sapiens | |
| 2 | C, D, J, K (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, L, M... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | H (A) | DIHYDROGENPHOSPHATE ION | non-polymer | 97.0 | 1 | Chemie (2HP) | |||
| 5 | I, O (A, B) | (2~{R})-2-[[4-[(4-aminocarbonylphenyl)carbonylamino]phenyl]sulfonylamino]-5-[(2~{S},4~{S})-4-azanyl-2-[[(2~{S})-1-[[(2~{S})-1-[(5-azanyl-5-oxidanylidene-pentyl)amino]-5-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]-methyl-amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxidanylidene-pentanoic acid | non-polymer | 916.0 | 2 | Chemie (L2U) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37619.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2431.1 | |
| All* | Total formula weight | 40050.9 |
