8H69
Cryo-EM structure of influenza RNA polymerase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 3 | RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3') | polymer | 18 | 5608.3 | 1 | Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) | ||
2 | 5 | RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*AP*GP*UP*UP*UP*U)-3') | polymer | 19 | 6150.7 | 1 | Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) | ||
3 | A | Polymerase acidic protein | polymer | 716 | 82669.5 | 1 | UniProt (Q91R78) Pfam (PF00603) UniProt (by SIFTS) (Q9Q0U9) In PDB | Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) | |
4 | B | RNA-directed RNA polymerase catalytic subunit | polymer | 757 | 86492.2 | 1 | UniProt (Q91HA4) Pfam (PF00602) UniProt (by SIFTS) (Q9Q0V0) In PDB | Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) | |
5 | C | Polymerase basic protein 2 | polymer | 759 | 85954.0 | 1 | UniProt (Q6E3M8) Pfam (PF20947) Pfam (PF20948) Pfam (PF20949) Pfam (PF20950) Pfam (PF00604) Pfam (PF20951) Pfam (PF20952) UniProt (by SIFTS) (Q9Q0V1) In PDB | Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) | RNA-directed RNA polymerase subunit P3 |
Sequence modifications
A: 1 - 716 (UniProt: Q91R78)
B: 1 - 757 (UniProt: Q91HA4)
C: 1 - 759 (UniProt: Q6E3M8)
PDB | External Database | Details |
---|---|---|
Val 100 | Ile 100 | conflict |
Thr 567 | Ala 567 | conflict |
PDB | External Database | Details |
---|---|---|
Glu 148 | Gly 148 | conflict |
PDB | External Database | Details |
---|---|---|
Thr 106 | Lys 106 | conflict |
Glu 358 | Asp 358 | conflict |
Arg 641 | Gly 641 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 266874.7 | |
All* | Total formula weight | 266874.7 |