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8H4I

DHA-bound FFAR4 in complex with Gs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
engineered mini Galpha-S subunitpolymer36141879.51Pfam (PF00503)
UniProt (by SIFTS) (P63092)
UniProt (by SIFTS) (P63096)
Homo sapiens (human)
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34537915.51UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)
3C
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
4D
(D)
Nb35polymer16117381.61Lama glama (llama)
5E
(R)
Free fatty acid receptor 4polymer36140533.21UniProt (Q5NUL3)
Pfam (PF00001)
Homo sapiens (human)G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1
6F
(R)
DOCOSA-4,7,10,13,16,19-HEXAENOIC ACIDnon-polymer328.51Chemie (HXA)
Sequence modifications
B: 2 - 340 (UniProt: P62873)
PDBExternal DatabaseDetails
Met -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Leu -1-expression tag
Leu 0-expression tag
Gln 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight145570.9
Non-Polymers*Number of molecules1
Total formula weight328.5
All*Total formula weight145899.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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