8H34
Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 hexameric complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, J, O... (M, O, C, F, I...) | Cullin-3 | polymer | 768 | 89063.3 | 6 | UniProt (Q13618) Pfam (PF00888) Pfam (PF10557) | Homo sapiens (human) | CUL-3 |
| 2 | C, D, H, I, M... (P, N, A, B, G...) | Kelch repeat and BTB domain-containing protein 2 | polymer | 623 | 71403.4 | 6 | UniProt (Q8IY47) Pfam (PF00651) Pfam (PF07707) Pfam (PF01344) | Homo sapiens (human) | |
| 3 | E, F, K, L, Q... (R, Q, E, D, L...) | E3 ubiquitin-protein ligase RBX1 | polymer | 121 | 13970.8 | 6 | UniProt (P62877) Pfam (PF12678) | Homo sapiens (human) | E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1 |
| 4 | AA, BA, CA, DA, EA... (E, D, L, K, R...) | ZINC ION | non-polymer | 65.4 | 18 | Chemie (ZN) |
Sequence modifications
R, Q, E, D, L, K: 1 - 108 (UniProt: P62877)
| PDB | External Database | Details |
|---|---|---|
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 1046624.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1177.4 | |
| All* | Total formula weight | 1047802.1 |
