8GZ2
Cryo-EM structure of human NaV1.6/beta1/beta2-4,9-anhydro-tetrodotoxin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Sodium channel subunit beta-1 | polymer | 218 | 24732.1 | 1 | UniProt (Q07699) Pfam (PF07686) | Homo sapiens (human) | |
| 2 | B (B) | Sodium channel protein type 8 subunit alpha | polymer | 1980 | 225520.6 | 1 | UniProt (Q9UQD0) Pfam (PF00520) Pfam (PF11933) Pfam (PF06512) Pfam (PF00612) | Homo sapiens (human) | Sodium channel protein type VIII subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.6 |
| 3 | C (C) | Sodium channel subunit beta-2 | polymer | 215 | 24355.9 | 1 | UniProt (O60939) Pfam (PF07686) | Homo sapiens (human) | |
| 4 | D, E, F, G, H (A, E, F, G, H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 5 | I, J (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | K (B) | (1R,2S,3S,4R,5R,9S,11S,12S,14R)-7-amino-2,4,12-trihydroxy-2-(hydroxymethyl)-10,13,15-trioxa-6,8-diazapentacyclo[7.4.1.1~3,12~.0~5,11~.0~5,14~]pentadec-7-en-8-ium (non-preferred name) | non-polymer | 301.3 | 1 | Chemie (WMK) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 274608.6 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2932.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 743.7 | |
| All* | Total formula weight | 278285.0 |
