8GYE

Crystal Structure of the 4-1BB in complex with ZG033 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, D)	Tumor necrosis factor receptor superfamily member 9	polymer	174	18541.8	2	UniProt (Q07011) Pfam (PF00020)	Homo sapiens (Human)	4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA
2	C, E (B, E)	ZG033 Fab H chain	polymer	220	23180.9	2		Homo sapiens
3	D, F (C, F)	ZG033 Fab L chain	polymer	214	23443.0	2		Homo sapiens
4	G, H (A, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	I (E)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	J, K, L, M, N... (A, D, B, C, E...)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, D: 24 - 186 (UniProt: Q07011)

PDB	External Database	Details
Leu 187	-	expression tag
Glu 188	-	expression tag
Gly 189	-	expression tag
Gly 190	-	expression tag
Gly 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	130331.2
Non-Polymers*	Number of molecules	3
	Total formula weight	534.5
All*	Total formula weight	130865.7

*Water molecules are not included.