8GY5
High-resolution structure of the cemiplimab Fab in complex with PD-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, H) | heavy chain | polymer | 229 | 24493.4 | 2 | Homo sapiens | ||
| 2 | B, E (B, L) | light chain | polymer | 214 | 23274.7 | 2 | Homo sapiens | ||
| 3 | C, F (Q, P) | Programmed cell death protein 1 | polymer | 125 | 14083.6 | 2 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (human) | Protein PD-1,hPD-1 |
| 4 | G, H, I, J, K... (A, B, Q, H, L...) | water | water | 18.0 | 644 | Chemie (HOH) |
Sequence modifications
Q, P: 26 - 150 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Ser 93 | Cys 93 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 123703.6 | |
| All* | Total formula weight | 123703.6 |
