8GY5

High-resolution structure of the cemiplimab Fab in complex with PD-1

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0016020	cellular_component	membrane
P	0050777	biological_process	negative regulation of immune response
Q	0016020	cellular_component	membrane
Q	0050777	biological_process	negative regulation of immune response

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR198-HIS204
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:28165004

Chain	Residue	Details
Q	ASN49
Q	ASN74
Q	ASN116
P	ASN49
P	ASN74
P	ASN116

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28165004, ECO:0007744|PDB:5WT9

Chain	Residue	Details
Q	ASN58
P	ASN58

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