8GWK

SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase	polymer	932	106781.0	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680)	Severe acute respiratory syndrome coronavirus 2	Pol, RdRp, Non-structural protein 12, nsp12
2	B, D (B, D)	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717)	Severe acute respiratory syndrome coronavirus 2	nsp8
3	C (C)	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTC1) Pfam (PF08716)	Severe acute respiratory syndrome coronavirus 2	nsp7
4	E (I)	primer	polymer	25	8172.9	1		Severe acute respiratory syndrome coronavirus 2
5	F (J)	template	polymer	26	8215.9	1		Severe acute respiratory syndrome coronavirus 2
6	G, H (E, F)	Helicase	polymer	601	66930.5	2	UniProt (P0DTD1) Pfam (PF20632) Pfam (PF20633) Pfam (PF20631) Pfam (PF13087)	Severe acute respiratory syndrome coronavirus 2	Hel, Non-structural protein 13, nsp13
7	I (G)	Non-structural protein 9	polymer	113	12391.2	1	UniProt (P0DTD1) Pfam (PF08710)	Severe acute respiratory syndrome coronavirus 2	nsp9
8	J, K, N, O, P... (A, E, F)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
9	L (A)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	1	Chemie (GNP)
10	M (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
11	T (G)	[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate	non-polymer		371.2	1	Chemie (F86)
12	U, V (A, G)	water	water		18.0	6	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	322477.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1441.0
All*	Total formula weight	323918.0

*Water molecules are not included.