8GVM
The structure of azide-bound cytochrome C oxidase determined using the crystals exposed to 20 mm azide solution for 4 days
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N (A, N) | Cytochrome c oxidase subunit 1 | polymer | 514 | 57093.9 | 2 | UniProt (P00396) Pfam (PF00115) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide I |
| 2 | B, O (B, O) | Cytochrome c oxidase subunit 2 | polymer | 227 | 26068.4 | 2 | UniProt (P68530) Pfam (PF02790) Pfam (PF00116) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide II |
| 3 | C, P (C, P) | Cytochrome c oxidase subunit 3 | polymer | 261 | 29957.6 | 2 | UniProt (P00415) Pfam (PF00510) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide III |
| 4 | D, Q (D, Q) | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | polymer | 147 | 17179.6 | 2 | UniProt (P00423) Pfam (PF02936) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1 |
| 5 | E, R (E, R) | Cytochrome c oxidase subunit 5A | polymer | 109 | 12453.1 | 2 | UniProt (P00426) Pfam (PF02284) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide Va |
| 6 | F, S (F, S) | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 98 | 10684.0 | 2 | UniProt (P00428) Pfam (PF01215) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIa,Cytochrome c oxidase polypeptide Vb |
| 7 | G, T (G, T) | Cytochrome c oxidase subunit 6A2, mitochondrial | polymer | 85 | 9629.8 | 2 | UniProt (P07471) Pfam (PF02046) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIa-heart,COXVIAH,Cytochrome c oxidase polypeptide VIb |
| 8 | H, U (H, U) | Cytochrome c oxidase subunit 6B1 | polymer | 85 | 10039.2 | 2 | UniProt (P00429) Pfam (PF02297) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1 |
| 9 | I, V (I, V) | Cytochrome c oxidase subunit 6C | polymer | 74 | 8521.0 | 2 | UniProt (P04038) Pfam (PF02937) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit STA |
| 10 | J, W (J, W) | Cytochrome c oxidase subunit 7A1 | polymer | 59 | 6682.7 | 2 | UniProt (P07470) Pfam (PF02238) | Bos taurus (domestic cattle) | Cytochrome c oxidase subunit VIIIc,VIIIC |
| 11 | K, X (K, X) | Cytochrome c oxidase subunit 7B, mitochondrial | polymer | 56 | 6365.2 | 2 | UniProt (P13183) Pfam (PF05392) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIIb,IHQ |
| 12 | L, Y (L, Y) | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 47 | 5449.4 | 2 | UniProt (P00430) Pfam (PF02935) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIIIA |
| 13 | M, Z (M, Z) | Cytochrome c oxidase subunit 8B, mitochondrial | polymer | 46 | 4967.8 | 2 | UniProt (P10175) Pfam (PF02285) | Bos taurus (domestic cattle) | Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8H,IX,VIIIb |
| 14 | AA, BA, WC, XC (A, N) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 15 | CA, YC (A, N) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) PubChem (27099) | |||
| 16 | DA, ZC (A, N) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 17 | AD, BB, EA, UD (N, C, A, P) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 18 | BD, CD, FA, GA (N, A) | AZIDE ION | non-polymer | 42.0 | 4 | Chemie (AZI) PubChem (33558) | |||
| 19 | CB, DD, GB, HA, IA... (C, N, A, G, P) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 8 | Chemie (PGV) PubChem (21158857) PubChem (73746220) PubChem (5289145) PubChem (162368821) PubChem (163029036) | |||
| 20 | AC, BC, BE, CE, DC... (E, P, F, N, Q...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 67 | Chemie (EDO) | |||
| 21 | ED, FE, RC, SB, TA... (N, Q, L, D, B...) | TRISTEAROYLGLYCEROL | non-polymer | 891.5 | 6 | Chemie (TGL) PubChem (11146) | |||
| 22 | EB, JC, QC, TD, UA... (C, G, J, P, B...) | CHOLIC ACID | non-polymer | 408.6 | 8 | Chemie (CHD) PubChem (16401672) PubChem (16758100) PubChem (18528842) PubChem (20638765) PubChem (303) PubChem (23636694) PubChem (23640631) PubChem (6676) PubChem (23876184) PubChem (24836753) PubChem (24883735) PubChem (43835083) PubChem (16401251) PubChem (44135469) PubChem (44629918) PubChem (44657327) PubChem (21139644) PubChem (45114537) PubChem (45382168) PubChem (122340) PubChem (1762378) PubChem (46397523) PubChem (46783697) PubChem (49791911) PubChem (49796810) PubChem (50989873) PubChem (51432410) PubChem (51546373) PubChem (53298695) PubChem (53393606) PubChem (53477699) PubChem (160636) PubChem (221493) PubChem (57937243) PubChem (44339334) PubChem (58133002) PubChem (58582306) PubChem (376829) PubChem (439520) PubChem (58984417) PubChem (59032051) PubChem (59316662) PubChem (59877711) PubChem (59963674) PubChem (59997751) PubChem (60076012) PubChem (60098994) PubChem (60114995) PubChem (440427) PubChem (46780112) PubChem (66678354) PubChem (68097396) PubChem (68131418) PubChem (68318251) PubChem (68338620) PubChem (68372213) PubChem (71260265) PubChem (70649328) PubChem (70824975) PubChem (70930320) PubChem (70930789) PubChem (70960845) PubChem (637625) PubChem (59130005) PubChem (59381614) PubChem (59903914) PubChem (67122255) PubChem (3246132) PubChem (69904012) PubChem (130213) PubChem (145883) PubChem (70866085) PubChem (71001249) PubChem (239672) PubChem (71314856) PubChem (71752895) PubChem (5283869) PubChem (5283870) PubChem (5283871) PubChem (5283873) PubChem (5283875) PubChem (5283877) PubChem (5283878) PubChem (74765127) PubChem (89830646) PubChem (5302608) PubChem (5315844) PubChem (91128541) PubChem (91810856) PubChem (5283876) PubChem (5283879) PubChem (5283880) PubChem (5283872) PubChem (5283874) PubChem (98044963) PubChem (99565617) PubChem (122645815) PubChem (124161889) PubChem (124318072) PubChem (124488681) PubChem (125037036) PubChem (126577457) PubChem (129274856) PubChem (129274855) PubChem (129359810) PubChem (6708709) PubChem (6850901) PubChem (6850905) PubChem (99564899) PubChem (99565857) PubChem (133135020) PubChem (133126746) PubChem (11350342) PubChem (117684834) PubChem (117767695) PubChem (117944573) PubChem (118241311) PubChem (9802771) PubChem (121232934) PubChem (9846429) PubChem (9866174) PubChem (122537896) PubChem (122537897) PubChem (122644681) PubChem (122644923) PubChem (122646384) PubChem (12303168) PubChem (13020196) PubChem (71172094) PubChem (124328806) PubChem (124364505) PubChem (124425250) PubChem (124488680) PubChem (124511215) PubChem (124518077) PubChem (124518078) PubChem (124518446) PubChem (124761950) PubChem (12080557) PubChem (12303167) PubChem (12303172) PubChem (12303175) PubChem (12303178) PubChem (12303180) PubChem (13020205) PubChem (124841930) PubChem (124896923) PubChem (124896924) PubChem (124896925) PubChem (124896926) PubChem (124904187) PubChem (124904188) PubChem (124906682) PubChem (124906683) PubChem (124914603) PubChem (124914604) PubChem (124914605) PubChem (124914606) PubChem (125027431) PubChem (125037037) PubChem (162771689) PubChem (163059393) PubChem (163059399) PubChem (163059389) PubChem (126422551) PubChem (126422552) PubChem (126577461) PubChem (126672319) PubChem (166858402) PubChem (126969154) PubChem (129106816) PubChem (129460958) PubChem (129600748) PubChem (129628082) PubChem (130220803) PubChem (131700165) PubChem (132441695) PubChem (133548348) PubChem (133612061) PubChem (133655733) PubChem (133687870) PubChem (133688934) PubChem (134462403) PubChem (134555902) PubChem (134866321) PubChem (135373095) PubChem (137474142) PubChem (138107312) PubChem (139248576) PubChem (139291795) PubChem (139372812) PubChem (140618124) PubChem (141854542) PubChem (142134118) PubChem (143658950) PubChem (144316980) PubChem (145264188) PubChem (145714625) PubChem (146030145) PubChem (146665897) PubChem (154033190) PubChem (154036252) PubChem (154747009) PubChem (154825357) PubChem (155275443) PubChem (155605940) PubChem (157048615) PubChem (157269375) PubChem (157351909) PubChem (157383333) PubChem (158041002) PubChem (158420924) PubChem (158675416) PubChem (160081178) PubChem (160743345) PubChem (160917187) PubChem (161973449) PubChem (163059390) PubChem (163059391) PubChem (163059392) PubChem (163059394) PubChem (163059395) PubChem (163059396) PubChem (163059397) PubChem (163059398) PubChem (163059400) PubChem (163452349) PubChem (163452350) PubChem (163452351) PubChem (167344826) PubChem (168841979) PubChem (168841990) PubChem (168845540) PubChem (169410142) PubChem (169436432) PubChem (171721516) PubChem (157060709) | |||
| 23 | OD, VA (O, B) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 24 | PD, WA (O, B) | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) PubChem (122219) PubChem (46936343) PubChem (53962049) PubChem (446962) PubChem (5313189) PubChem (5313191) PubChem (5289212) PubChem (5313188) PubChem (5313190) PubChem (124586127) | |||
| 25 | AB, AE, HB, IB, SC... (C, P, L, M, Z) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 9 | Chemie (DMU) PubChem (24776995) PubChem (16396531) PubChem (45253991) PubChem (45254001) PubChem (24802064) PubChem (56845266) PubChem (58112552) PubChem (45253971) PubChem (59518661) PubChem (49866911) PubChem (70796430) PubChem (70839938) PubChem (71307274) PubChem (3637526) PubChem (5288091) PubChem (95370473) PubChem (98046563) PubChem (5288728) PubChem (101207920) PubChem (126735852) PubChem (95370474) PubChem (95370475) PubChem (95370476) PubChem (98046559) PubChem (98046561) PubChem (100941450) PubChem (100950626) PubChem (102219024) PubChem (118704896) PubChem (123134571) PubChem (124867949) PubChem (124867950) PubChem (124867951) PubChem (124867952) PubChem (126731012) PubChem (126731036) PubChem (126735974) PubChem (168490163) | |||
| 26 | DB, TE, VC, WD (C, T, N, P) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 27 | EE, FB, IC, KC, RB... (P, C, G, T) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 6 | Chemie (PEK) PubChem (21158855) PubChem (44552596) PubChem (45253969) PubChem (45253978) PubChem (53301835) PubChem (72280040) PubChem (53652586) PubChem (73659094) PubChem (5289133) PubChem (123132887) PubChem (9546819) PubChem (6426736) PubChem (134812608) PubChem (9546829) PubChem (9546830) PubChem (145998242) PubChem (156613384) PubChem (162679672) | |||
| 28 | CC, PE (F, S) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 29 | AF, BF, CF, DF, EF... (A, B, C, D, E...) | water | water | 18.0 | 1623 | Chemie (HOH) |
Sequence modifications
I, V: 1 - 73 (UniProt: P04038)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 410183.6 | |
| Non-Polymers* | Number of molecules | 130 |
| Total formula weight | 39325.8 | |
| All* | Total formula weight | 449509.4 |
