8GVM
The structure of azide-bound cytochrome C oxidase determined using the crystals exposed to 20 mm azide solution for 4 days
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N (A, N) | Cytochrome c oxidase subunit 1 | polymer | 514 | 57093.9 | 2 | UniProt (P00396) Pfam (PF00115) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide I |
| 2 | B, O (B, O) | Cytochrome c oxidase subunit 2 | polymer | 227 | 26068.4 | 2 | UniProt (P68530) Pfam (PF02790) Pfam (PF00116) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide II |
| 3 | C, P (C, P) | Cytochrome c oxidase subunit 3 | polymer | 261 | 29957.6 | 2 | UniProt (P00415) Pfam (PF00510) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide III |
| 4 | D, Q (D, Q) | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | polymer | 147 | 17179.6 | 2 | UniProt (P00423) Pfam (PF02936) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1 |
| 5 | E, R (E, R) | Cytochrome c oxidase subunit 5A | polymer | 109 | 12453.1 | 2 | UniProt (P00426) Pfam (PF02284) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide Va |
| 6 | F, S (F, S) | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 98 | 10684.0 | 2 | UniProt (P00428) Pfam (PF01215) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIa,Cytochrome c oxidase polypeptide Vb |
| 7 | G, T (G, T) | Cytochrome c oxidase subunit 6A2, mitochondrial | polymer | 85 | 9629.8 | 2 | UniProt (P07471) Pfam (PF02046) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIa-heart,COXVIAH,Cytochrome c oxidase polypeptide VIb |
| 8 | H, U (H, U) | Cytochrome c oxidase subunit 6B1 | polymer | 85 | 10039.2 | 2 | UniProt (P00429) Pfam (PF02297) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1 |
| 9 | I, V (I, V) | Cytochrome c oxidase subunit 6C | polymer | 73 | 8537.0 | 2 | UniProt (P04038) Pfam (PF02937) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit STA |
| 10 | J, W (J, W) | Cytochrome c oxidase subunit 7A1 | polymer | 59 | 6682.7 | 2 | UniProt (P07470) Pfam (PF02238) | Bos taurus (cattle) | Cytochrome c oxidase subunit VIIIc,VIIIC |
| 11 | K, X (K, X) | Cytochrome c oxidase subunit 7B, mitochondrial | polymer | 56 | 6365.2 | 2 | UniProt (P13183) Pfam (PF05392) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIIb,IHQ |
| 12 | L, Y (L, Y) | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 47 | 5449.4 | 2 | UniProt (P00430) Pfam (PF02935) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIIIA |
| 13 | M, Z (M, Z) | Cytochrome c oxidase subunit 8B, mitochondrial | polymer | 46 | 4967.8 | 2 | UniProt (P10175) Pfam (PF02285) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8H,IX,VIIIb |
| 14 | AA, BA, WC, XC (A, N) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 15 | CA, YC (A, N) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 16 | DA, ZC (A, N) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 17 | AD, BB, EA, UD (N, C, A, P) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 18 | BD, CD, FA, GA (N, A) | AZIDE ION | non-polymer | 42.0 | 4 | Chemie (AZI) | |||
| 19 | CB, DD, GB, HA, IA... (C, N, A, G, P) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 8 | Chemie (PGV) | |||
| 20 | AC, BC, BE, CE, DC... (E, P, F, N, Q...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 67 | Chemie (EDO) | |||
| 21 | ED, FE, RC, SB, TA... (N, Q, L, D, B...) | TRISTEAROYLGLYCEROL | non-polymer | 891.5 | 6 | Chemie (TGL) | |||
| 22 | EB, JC, QC, TD, UA... (C, G, J, P, B...) | CHOLIC ACID | non-polymer | 408.6 | 8 | Chemie (CHD) | |||
| 23 | OD, VA (O, B) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 24 | PD, WA (O, B) | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) | |||
| 25 | AB, AE, HB, IB, SC... (C, P, L, M, Z) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 9 | Chemie (DMU) | |||
| 26 | DB, TE, VC, WD (C, T, N, P) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) | |||
| 27 | EE, FB, IC, KC, RB... (P, C, G, T) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 6 | Chemie (PEK) | |||
| 28 | CC, PE (F, S) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 29 | AF, BF, CF, DF, EF... (A, B, C, D, E...) | water | water | 18.0 | 1623 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 410215.6 | |
| Non-Polymers* | Number of molecules | 130 |
| Total formula weight | 39325.8 | |
| All* | Total formula weight | 449541.4 |
