8GV3
The cryo-EM structure of GSNOR with NYY001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Alcohol dehydrogenase class-3 | polymer | 375 | 39901.3 | 2 | UniProt (P11766) Pfam (PF08240) Pfam (PF00107) In PDB | Homo sapiens (human) | Alcohol dehydrogenase 5,Alcohol dehydrogenase class chi chain,Alcohol dehydrogenase class-III,Glutathione-dependent formaldehyde dehydrogenase,FALDH,FDH,GSH-FDH,S-(hydroxymethyl)glutathione dehydrogenase |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | A, B | (4P)-4-{2-[4-(1H-imidazol-1-yl)phenyl]-5-[3-oxo-3-(2-oxo-1,3-thiazolidin-3-yl)propyl]-1H-pyrrol-1-yl}-3-methylbenzamide | non-polymer | 499.6 | 2 | Chemie (WKZ) |
Sequence modifications
A, B: 0 - 373 (UniProt: P11766)
| PDB | External Database | Details |
|---|---|---|
| Glu 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79802.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2587.7 | |
| All* | Total formula weight | 82390.3 |
