8GTT

Cryo-EM structure of human Pannexin1 resembling Pannexin2 pore with W74R/R75Dmutations

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Pannexin-1	polymer	434	49127.9	7	UniProt (Q96RD7) Pfam (PF00876) In PDB	Homo sapiens (human)

Sequence modifications

A, B, C, D, E, F, G: 1 - 426 (UniProt: Q96RD7)

PDB	External Database	Details
Arg 74	Trp 74	engineered mutation
Asp 75	Arg 75	engineered mutation
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	343895.3
All*	Total formula weight	343895.3

*Water molecules are not included.