8GT9
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Beclin-2 | polymer | 96 | 10970.9 | 4 | UniProt (A8MW95) Pfam (PF17675) In PDB | Homo sapiens (human) | Beclin-1 autophagy-related pseudogene 1,Beclin-1-like protein 1 |
| 2 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 157 - 248 (UniProt: A8MW95)
| PDB | External Database | Details |
|---|---|---|
| Gly 153 | - | expression tag |
| Pro 154 | - | expression tag |
| Gly 155 | - | expression tag |
| Ser 156 | - | expression tag |
| Leu 243 | Arg 243 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43883.7 | |
| All* | Total formula weight | 43883.7 |
