8GIF
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Apical membrane antigen 1, rhoptry neck protein 2 chimera | polymer | 357 | 39392.9 | 1 | UniProt (Q7KQK5) UniProt (Q8IKV6) Pfam (PF02430) In PDB | Plasmodium falciparum 3D7 | Merozoite surface antigen |
| 2 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 4 - 164 (UniProt: Q7KQK5)
A: 175 - 213 (UniProt: Q8IKV6)
A: 218 - 348 (UniProt: Q7KQK5)
| PDB | External Database | Details |
|---|---|---|
| Glu 1 | - | expression tag |
| Thr 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ala 64 | Thr 164 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 214 | - | linker |
| Gly 215 | - | linker |
| Ser 216 | - | linker |
| Gly 217 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 165 | - | linker |
| Gly 166 | - | linker |
| Gly 167 | - | linker |
| Gly 168 | - | linker |
| Ser 169 | - | linker |
| Gly 170 | - | linker |
| Gly 171 | - | linker |
| Gly 172 | - | linker |
| Gly 173 | - | linker |
| Ser 174 | - | linker |
| Ala 233 | Thr 288 | engineered mutation |
| - | Lys 351 | deletion |
| - | Gln 352 | deletion |
| - | Tyr 353 | deletion |
| - | Glu 354 | deletion |
| - | Gln 355 | deletion |
| - | His 356 | deletion |
| - | Leu 357 | deletion |
| - | Thr 358 | deletion |
| - | Asp 359 | deletion |
| - | Tyr 360 | deletion |
| - | Glu 361 | deletion |
| - | Lys 362 | deletion |
| - | Ile 363 | deletion |
| - | Lys 364 | deletion |
| - | Glu 365 | deletion |
| - | Gly 366 | deletion |
| - | Phe 367 | deletion |
| - | Lys 368 | deletion |
| - | Asn 369 | deletion |
| - | Lys 370 | deletion |
| - | Asn 371 | deletion |
| - | Ala 372 | deletion |
| - | Ser 373 | deletion |
| - | Met 374 | deletion |
| - | Ile 375 | deletion |
| - | Lys 376 | deletion |
| - | Ser 377 | deletion |
| - | Ala 378 | deletion |
| - | Phe 379 | deletion |
| - | Leu 380 | deletion |
| - | Pro 381 | deletion |
| - | Thr 382 | deletion |
| - | Gly 383 | deletion |
| - | Ala 384 | deletion |
| - | Phe 385 | deletion |
| Gly 296 | Lys 386 | conflict |
| Gly 297 | Ala 387 | conflict |
| Ser 298 | Asp 388 | conflict |
| Gly 299 | Arg 389 | conflict |
| Ala 333 | Ser 423 | engineered mutation |
| Ala 334 | Ser 424 | engineered mutation |
| Gly 349 | - | expression tag |
| Thr 350 | - | expression tag |
| Lys 351 | - | expression tag |
| His 352 | - | expression tag |
| His 353 | - | expression tag |
| His 354 | - | expression tag |
| His 355 | - | expression tag |
| His 356 | - | expression tag |
| His 357 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39392.9 | |
| All* | Total formula weight | 39392.9 |
