8GID

Crystal structure of a strain-transcending single-component Plasmodium falciparum AMA1-RON2L structure-based design immunogen 1 (SBD1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Apical membrane antigen 1, rhoptry neck protein 2 chimera	polymer	377	41729.5	1	UniProt (D9MXR5) UniProt (Q7KQK5) UniProt (Q8IKV6) Pfam (PF02430) In PDB	Plasmodium falciparum 3D7	Merozoite surface antigen
2		water	water		18.0	164	Chemie (HOH)

Sequence modifications

A: 1 - 53 (UniProt: D9MXR5)

PDB	External Database	Details
Glu -2	-	expression tag
Thr -1	-	expression tag
Gly 0	-	expression tag
Ala 38	Ser 280	engineered mutation
Ala 39	Ser 281	engineered mutation
Gly 54	-	linker
Gly 55	-	linker
Gly 56	-	linker
Gly 57	-	linker
Ser 58	-	linker
Gly 59	-	linker
Gly 60	-	linker
Gly 61	-	linker
Gly 62	-	linker
Ser 63	-	linker
Gly 64	-	linker
Gly 65	-	linker
Gly 66	-	linker
Gly 67	-	linker
Ser 68	-	linker
Gly 69	-	linker
Gly 70	-	linker
Gly 71	-	linker
Gly 72	-	linker

A: 73 - 328 (UniProt: Q7KQK5)

PDB	External Database	Details
Ala 134	Thr 164	engineered mutation
Ala 258	Thr 288	engineered mutation

A: 329 - 365 (UniProt: Q8IKV6)

PDB	External Database	Details
Gly 366	-	expression tag
Thr 367	-	expression tag
Lys 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag
His 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41729.5
All*	Total formula weight	41729.5

*Water molecules are not included.