8GI7

C143A variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	citrate synthase (unknown stereospecificity)	polymer	379	40987.5	4	UniProt (A0A045JB88) Pfam (PF00285) UniProt (by SIFTS) (P9WPD3) In PDB	Mycobacterium tuberculosis H37Rv
2	A, B, C, D	CITRATE ANION	non-polymer		189.1	4	Chemie (FLC)
3	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
4		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 373 (UniProt: A0A045JB88)

PDB	External Database	Details
Ala 143	Cys 143	engineered mutation
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	163950.2
Non-Polymers*	Number of molecules	9
	Total formula weight	1066.7
All*	Total formula weight	165016.9

*Water molecules are not included.