8GH7
142D6 bound to BIR3-XIAP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase XIAP | polymer | 99 | 11369.7 | 2 | UniProt (P98170) Pfam (PF00653) | Homo sapiens (human) | Baculoviral IAP repeat-containing protein 4,IAP-like protein,ILP,hILP,Inhibitor of apoptosis protein 3,IAP-3,hIAP-3,hIAP3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein,X-linked IAP |
| 2 | C, D (D, H) | BIR3 inhibitor MAA-CHG-PRO-ZHW | polymer | 4 | 552.7 | 2 | BIRD (PRD_002528) | synthetic construct | |
| 3 | E, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, H (A, B) | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL | non-polymer | 310.4 | 2 | Chemie (7PE) | |||
| 5 | I, J, K, L (A, B, D, H) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 253 - 347 (UniProt: P98170)
| PDB | External Database | Details |
|---|---|---|
| Gly 249 | - | expression tag |
| Ser 250 | - | expression tag |
| His 251 | - | expression tag |
| Met 252 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 23844.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 751.6 | |
| All* | Total formula weight | 24596.3 |
