8GDV
Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Gag polyprotein | polymer | 231 | 25443.2 | 6 | UniProt (D2ECD8) Pfam (PF00607) Pfam (PF19317) UniProt (by SIFTS) (P12493) | Human immunodeficiency virus 1 | |
| 2 | G, H, I, J, K... (M, N, O, P, Q...) | Cleavage and polyadenylation specificity factor subunit 6 | polymer | 15 | 1550.8 | 6 | UniProt (by SIFTS) (Q16630) | Homo sapiens | |
| 3 | M, N (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) |
Sequence modifications
A, B, C, D, E, F: 1 - 231 (UniProt: D2ECD8)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| Ile 66 | Met 198 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 161964.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1320.1 | |
| All* | Total formula weight | 163284.3 |
