8GDU
Crystal structure of a mutant methyl transferase from Methanosarcina acetivorans, Northeast Structural Genomics Consortium (NESG) Target MvR53-11M
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methyltransferase domain-containing protein | polymer | 202 | 23371.5 | 1 | UniProt (Q8TNZ0) Pfam (PF13649) In PDB | Methanosarcina acetivorans C2A | |
2 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
3 | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 1 - 194 (UniProt: Q8TNZ0)
PDB | External Database | Details |
---|---|---|
Arg 8 | Lys 8 | engineered mutation |
Arg 52 | Lys 52 | engineered mutation |
Arg 64 | Lys 64 | engineered mutation |
Arg 65 | Asp 65 | engineered mutation |
Arg 71 | Lys 71 | engineered mutation |
Arg 126 | Lys 126 | engineered mutation |
Arg 129 | Lys 129 | engineered mutation |
Arg 133 | Lys 133 | engineered mutation |
Arg 142 | Lys 142 | engineered mutation |
Arg 155 | Lys 155 | engineered mutation |
Arg 172 | Lys 172 | engineered mutation |
Arg 194 | Lys 194 | engineered mutation |
Leu 195 | - | expression tag |
Glu 196 | - | expression tag |
His 197 | - | expression tag |
His 198 | - | expression tag |
His 199 | - | expression tag |
His 200 | - | expression tag |
His 201 | - | expression tag |
His 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23371.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 384.4 | |
All* | Total formula weight | 23755.9 |