8GBN
Structure of Apo Human SIRT5 P114T Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 271 | 29546.8 | 2 | UniProt (Q9NXA8) Pfam (PF02146) | Homo sapiens (human) | Regulatory protein SIR2 homolog 5,SIR2-like protein 5 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B: 32 - 302 (UniProt: Q9NXA8)
| PDB | External Database | Details |
|---|---|---|
| Thr 114 | Pro 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59093.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 255.0 | |
| All* | Total formula weight | 59348.5 |
