8GAB
Crystal structure of CTLA-4 in complex with a high affinity CTLA-4 binder
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | CTLA-4 binder | polymer | 109 | 12793.7 | 2 | synthetic construct | ||
| 2 | B, D (B, D) | Cytotoxic T-lymphocyte protein 4 | polymer | 126 | 13510.3 | 2 | UniProt (P16410) Pfam (PF07686) | Homo sapiens (human) | Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4 |
| 3 | E (D) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | F, G, H (B, C, D) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52608.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 39.1 | |
| All* | Total formula weight | 52647.1 |
