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8G88

Human Oct4 bound to nucleosome with human nMatn1 sequence

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3polymer13515303.92UniProt (P84233)
Pfam (PF00125)
Xenopus laevis (African clawed frog)
2B, F
(B, F)
Histone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
Xenopus laevis (African clawed frog)
3C, G
(C, G)
Histone H2Apolymer12913978.22UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
Xenopus laevis (African clawed frog)
4D, H
(D, H)
Histone H2Bpolymer12213524.82UniProt (P02281)
Pfam (PF00125)
Xenopus laevis (African clawed frog)H2B1.1
5I
(I)
nMATn1 DNA top strand (168-MER)polymer18656933.61Homo sapiens
6J
(J)
nMatn1 DNA bottom strand (168-MER)polymer18657889.91Homo sapiens
7K
(X)
POU domain, class 5, transcription factor 1polymer39542299.51UniProt (Q01860)
Pfam (PF00157)
Pfam (PF00046)
Homo sapiens (human)Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
PDBExternal DatabaseDetails
Ala 102Gly 103variant
D, H: 1 - 122 (UniProt: P02281)
PDBExternal DatabaseDetails
Thr 29Ser 33variant
X: 1 - 360 (UniProt: Q01860)
PDBExternal DatabaseDetails
Gly -34-expression tag
Ser -33-expression tag
Ser -32-expression tag
His -31-expression tag
His -30-expression tag
His -29-expression tag
His -28-expression tag
His -27-expression tag
His -26-expression tag
Ser -25-expression tag
Ser -24-expression tag
Gly -23-expression tag
Leu -22-expression tag
Val -21-expression tag
Pro -20-expression tag
Arg -19-expression tag
Gly -18-expression tag
Ser -17-expression tag
His -16-expression tag
Met -15-expression tag
Ala -14-expression tag
Ser -13-expression tag
Met -12-expression tag
Thr -11-expression tag
Gly -10-expression tag
Gly -9-expression tag
Gln -8-expression tag
Gln -7-expression tag
Met -6-expression tag
Gly -5-expression tag
Arg -4-expression tag
Asp -3-expression tag
Pro -2-expression tag
Asn -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight265263.2
All*Total formula weight265263.2
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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