8G6T

Bromodomain of CBP liganded with inhibitor iCBP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CREB-binding protein	polymer	116	13847.9	4	UniProt (Q92793) Pfam (PF00439)	Homo sapiens (human)	Histone lysine acetyltransferase CREBBP,Protein-lysine acetyltransferase CREBBP
2	E, F, G, I (A, B, C, D)	(6S)-1-(3,4-dibromophenyl)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one	non-polymer		656.4	4	Chemie (YRI)
3	H, J (C, D)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
4	K, L, M, N (A, B, C, D)	water	water		18.0	304	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55391.5
Non-Polymers*	Number of molecules	6
	Total formula weight	2743.0
All*	Total formula weight	58134.5

*Water molecules are not included.