8G6E
Structure of the Plasmodium falciparum 20S proteasome complexed with inhibitor TDI-8304
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (A, O) | Proteasome subunit alpha type-6 | polymer | 260 | 29531.7 | 2 | UniProt (W7JVP8) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 2 | B, P (B, P) | Proteasome subunit alpha type-2 | polymer | 235 | 26556.4 | 2 | UniProt (A0A2I0BQ13) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 3 | C, Q (C, Q) | Proteasome subunit alpha type | polymer | 246 | 27977.7 | 2 | UniProt (W7KN95) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 4 | D, R (D, R) | Proteasome subunit alpha type | polymer | 241 | 27263.3 | 2 | UniProt (A0A2I0BS43) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 5 | E, S (E, S) | Proteasome subunit alpha type | polymer | 256 | 28417.4 | 2 | UniProt (A0A2I0BP34) Pfam (PF00227) Pfam (PF10584) | Plasmodium falciparum NF54 | |
| 6 | F, T (F, T) | Proteasome subunit alpha type-1 | polymer | 253 | 28742.6 | 2 | UniProt (W7K5W7) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 7 | G, U (G, U) | Proteasome subunit alpha type-3 | polymer | 252 | 29324.3 | 2 | UniProt (W7K040) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 8 | H, V (H, V) | Proteasome subunit beta type-6 | polymer | 252 | 29143.9 | 2 | UniProt (W7JUG8) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 9 | I, W (I, W) | Proteasome subunit beta | polymer | 229 | 25104.9 | 2 | UniProt (W7K1J4) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 10 | J, X (J, X) | Proteasome subunit beta | polymer | 218 | 24533.1 | 2 | UniProt (A0A2I0BXS0) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 11 | K, Y (K, Y) | Proteasome subunit beta | polymer | 195 | 22889.1 | 2 | UniProt (W7JKG5) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 12 | L, Z (L, Z) | Proteasome subunit beta | polymer | 211 | 23620.6 | 2 | UniProt (W7K6A8) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 13 | AA, M (M, a) | Proteasome subunit beta | polymer | 240 | 27301.2 | 2 | UniProt (A0A2I0BU46) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 14 | BA, N (N, b) | Proteasome subunit beta | polymer | 265 | 30909.9 | 2 | UniProt (W7K6I2) Pfam (PF00227) | Plasmodium falciparum NF54 | |
| 15 | CA, DA, EA, FA, GA... (C, I, L, Q, W...) | (7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide | non-polymer | 597.7 | 6 | Chemie (YRE) | |||
| 16 | AB, BB, CB, DB, EB... (S, T, U, V, W...) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 762632.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3586.5 | |
| All* | Total formula weight | 766218.6 |
