8G4A
Human ARNT PAS-B complexed with KG-548 small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aryl hydrocarbon receptor nuclear translocator | polymer | 119 | 13956.7 | 2 | UniProt (P27540) Pfam (PF14598) | Homo sapiens (human) | ARNT protein,Class E basic helix-loop-helix protein 2,bHLHe2,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta |
| 2 | C (A) | 5-[3,5-bis(trifluoromethyl)phenyl]-2H-tetrazole | non-polymer | 282.1 | 1 | Chemie (YL8) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 356 - 470 (UniProt: P27540)
| PDB | External Database | Details |
|---|---|---|
| Gly 352 | - | expression tag |
| Ala 353 | - | expression tag |
| Met 354 | - | expression tag |
| Asp 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27913.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 282.1 | |
| All* | Total formula weight | 28195.5 |
