8G3C
Crystal structure of human WDR5 in complex with N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide (compound 1, WDR5-MYC PPI inhibitor)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 313 | 34391.0 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | B (A) | N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide | non-polymer | 360.4 | 1 | Chemie (YJN) | |||
| 3 | C (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34391.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 360.4 | |
| All* | Total formula weight | 34751.4 |
