8G2F

Crystal Structure of PRMT3 with Compound II710

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein arginine N-methyltransferase 3	polymer	340	38281.9	1	UniProt (O60678) Pfam (PF06325) Pfam (PF22528) In PDB	Homo sapiens (human)	Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
2	A	5'-S-[3-(N'-benzylcarbamimidamido)propyl]-5'-thioadenosine	non-polymer		472.6	1	Chemie (DVS)
3		water	water		18.0	42	Chemie (HOH)

Sequence modifications

A: 211 - 531 (UniProt: O60678)

PDB	External Database	Details
Met 192	-	initiating methionine
Gly 193	-	expression tag
Ser 194	-	expression tag
Ser 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
Ser 202	-	expression tag
Ser 203	-	expression tag
Gly 204	-	expression tag
Leu 205	-	expression tag
Val 206	-	expression tag
Pro 207	-	expression tag
Arg 208	-	expression tag
Gly 209	-	expression tag
Ser 210	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38281.9
Non-Polymers*	Number of molecules	1
	Total formula weight	472.6
All*	Total formula weight	38754.5

*Water molecules are not included.