8FZK
Dimeric human importin alpha subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Importin subunit alpha-1 | polymer | 460 | 49792.4 | 4 | UniProt (P52292) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) | Homo sapiens (human) | Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha |
| 2 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | F (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 71 - 529 (UniProt: P52292)
| PDB | External Database | Details |
|---|---|---|
| Ser 70 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 199169.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 219.5 | |
| All* | Total formula weight | 199389.3 |
