8FZ3
Sterile Alpha Motif of Human Translocation ETS Leukemia, Non-Polymer Crystal Form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Transcription factor ETV6, Activated CDC42 kinase 1 fusion | polymer | 170 | 19810.5 | 4 | UniProt (P41212) UniProt (Q07912) Pfam (PF02198) In PDB | Homo sapiens (human) | ETS translocation variant 6,ETS-related protein Tel1,Tel,ACK-1,Tyrosine kinase non-receptor protein 2 |
2 | A, C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 12 - 88 (UniProt: P41212)
A, B, C, D: 90 - 170 (UniProt: Q07912)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
Ser 45 | Arg 80 | engineered mutation |
Glu 77 | Val 112 | engineered mutation |
Gly 89 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 79242.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 165.9 | |
All* | Total formula weight | 79407.9 |