8FZ3

Sterile Alpha Motif of Human Translocation ETS Leukemia, Non-Polymer Crystal Form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
A	0007165	biological_process	signal transduction
A	0016310	biological_process	phosphorylation
A	0043565	molecular_function	sequence-specific DNA binding
B	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
B	0007165	biological_process	signal transduction
B	0016310	biological_process	phosphorylation
B	0043565	molecular_function	sequence-specific DNA binding
C	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
C	0007165	biological_process	signal transduction
C	0016310	biological_process	phosphorylation
C	0043565	molecular_function	sequence-specific DNA binding
D	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
D	0007165	biological_process	signal transduction
D	0016310	biological_process	phosphorylation
D	0043565	molecular_function	sequence-specific DNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Breakpoint for translocation to form ETV6-MDS2 in MDS

Chain	Residue	Details
A	LEU19
B	LEU19
C	LEU19
D	LEU19

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Breakpoint for translocation to form PAX5-ETV6

Chain	Residue	Details
A	ARG20
B	ARG20
C	ARG20
D	ARG20

---