8FXZ
Cryo-EM structure of cowpox virus M2 in complex with human B7.1 (heptameric ring)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, B, D, F, I...) | CPXV040 protein | polymer | 206 | 23682.7 | 7 | UniProt (Q8QN22) Pfam (PF04887) | Cowpox virus (Brighton Red) | |
| 2 | B, D, F, H, J... (H, C, E, G, J...) | T-lymphocyte activation antigen CD80 | polymer | 201 | 22993.1 | 7 | UniProt (P33681) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (human) | Activation B7-1 antigen,BB1,CTLA-4 counter-receptor B7.1,B7 |
| 3 | AA, BA, CA, DA, EA... (I, K, M, A, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
A, B, D, F, I, K, M: 18 - 220 (UniProt: Q8QN22)
H, C, E, G, J, L, N: 1 - 201 (UniProt: P33681)
| PDB | External Database | Details |
|---|---|---|
| Lys 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Glu 17 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 200 | Thr 234 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 326730.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4645.4 | |
| All* | Total formula weight | 331376.2 |
