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8FXZ

Cryo-EM structure of cowpox virus M2 in complex with human B7.1 (heptameric ring)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0044165cellular_componenthost cell endoplasmic reticulum
A0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
B0005576cellular_componentextracellular region
B0044165cellular_componenthost cell endoplasmic reticulum
B0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
C0015026molecular_functioncoreceptor activity
C0031295biological_processT cell costimulation
D0005576cellular_componentextracellular region
D0044165cellular_componenthost cell endoplasmic reticulum
D0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
E0015026molecular_functioncoreceptor activity
E0031295biological_processT cell costimulation
F0005576cellular_componentextracellular region
F0044165cellular_componenthost cell endoplasmic reticulum
F0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
G0015026molecular_functioncoreceptor activity
G0031295biological_processT cell costimulation
H0015026molecular_functioncoreceptor activity
H0031295biological_processT cell costimulation
I0005576cellular_componentextracellular region
I0044165cellular_componenthost cell endoplasmic reticulum
I0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
J0015026molecular_functioncoreceptor activity
J0031295biological_processT cell costimulation
K0005576cellular_componentextracellular region
K0044165cellular_componenthost cell endoplasmic reticulum
K0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
L0015026molecular_functioncoreceptor activity
L0031295biological_processT cell costimulation
M0005576cellular_componentextracellular region
M0044165cellular_componenthost cell endoplasmic reticulum
M0085034biological_processsymbiont-mediated suppression of host NF-kappaB cascade
N0015026molecular_functioncoreceptor activity
N0031295biological_processT cell costimulation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues700
DetailsDomain: {"description":"Ig-like V-type"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues14
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11279502","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues7
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2025-07-23

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