8FW2
Cryo-EM structure of full-length human NLRC4 inflammasome with C11 symmetry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | NLR family CARD domain-containing protein 4 | polymer | 1030 | 117027.7 | 3 | UniProt (Q9NPP4) Pfam (PF00619) Pfam (PF05729) Pfam (PF22524) Pfam (PF17889) | Homo sapiens (human) | CARD,LRR,and NACHT-containing protein,CED-4-like protein Clan,Caspase recruitment domain-containing protein 12,Ice protease-activating factor,Ipaf |
Sequence modifications
A, B, C: 1 - 1024 (UniProt: Q9NPP4)
| PDB | External Database | Details |
|---|---|---|
| Ala -5 | - | expression tag |
| Glu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Cys -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Asn 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 351083.0 | |
| All* | Total formula weight | 351083.0 |
