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8FVM

PCSK9 in complex with an inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proprotein convertase subtilisin/kexin type 9polymer15217035.51UniProt (Q8NBP7)
Pfam (PF05922)
Homo sapiens (human)Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9
2B
(B)
Proprotein convertase subtilisin/kexin type 9polymer54057443.71UniProt (Q8NBP7)
Pfam (PF00082)
Pfam (PF18459)
Pfam (PF18464)
Pfam (PF18463)
Homo sapiens (human)Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9
3C
(C)
DGN-DVA-YC3-GLU-PRO-THR-THR-PHE-MAA-A1BC0 inhibitorpolymer101305.61BIRD (PRD_002558)synthetic construct
4D
(B)
CALCIUM IONnon-polymer40.11Chemie (CA)
Sequence modifications
B: 153 - 692 (UniProt: Q8NBP7)
PDBExternal DatabaseDetails
Ile 474Val 474variant
Glu 670Gly 670variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight75784.7
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight75824.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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