8FVJ
Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 0, 5 | Core-binding factor subunit beta | polymer | 157 | 18643.8 | 2 | UniProt (Q13951) Pfam (PF02312) In PDB | Homo sapiens (human) | CBF-beta,Polyomavirus enhancer-binding protein 2 beta subunit,PEA2-beta,PEBP2-beta,SL3-3 enhancer factor 1 subunit beta,SL3/AKV core-binding factor beta subunit |
2 | 1, 6 | Virion infectivity factor | polymer | 178 | 21160.5 | 2 | UniProt (P12504) Pfam (PF00559) In PDB | Human immunodeficiency virus 1 | Vif,SOR protein |
3 | 3, 8 | Elongin-B | polymer | 102 | 11488.0 | 2 | UniProt (Q15370) Pfam (PF00240) In PDB | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
4 | 4, 9 | Elongin-C | polymer | 96 | 10843.4 | 2 | UniProt (Q15369) Pfam (PF03931) In PDB | Homo sapiens (human) | EloC, Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Transcription elongation factor B polypeptide 1 |
5 | 2, 7 | Cullin-5 | polymer | 314 | 36614.0 | 2 | UniProt (Q93034) Pfam (PF00888) In PDB | Homo sapiens (human) | CUL-5,Vasopressin-activated calcium-mobilizing receptor 1,VACM-1 |
6 | 1, 6 | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
1, 6: 1 - 177 (UniProt: P12504)
2, 7: 10 - 320 (UniProt: Q93034)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Pro 0 | - | expression tag |
His 48 | Asn 48 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 7 | - | expression tag |
Pro 8 | - | expression tag |
Ala 9 | - | expression tag |
Ser 11 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 197499.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 197630.2 |