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8FVJ

Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5

Functional Information from GO Data
ChainGOidnamespacecontents
00003713molecular_functiontranscription coactivator activity
00005634cellular_componentnucleus
10003723molecular_functionRNA binding
10005515molecular_functionprotein binding
10016020cellular_componentmembrane
10019058biological_processviral life cycle
10020002cellular_componenthost cell plasma membrane
10030430cellular_componenthost cell cytoplasm
10044423cellular_componentvirion component
20006511biological_processubiquitin-dependent protein catabolic process
20031625molecular_functionubiquitin protein ligase binding
30006368biological_processtranscription elongation by RNA polymerase II
30030891cellular_componentVCB complex
30070449cellular_componentelongin complex
40006511biological_processubiquitin-dependent protein catabolic process
50003713molecular_functiontranscription coactivator activity
50005634cellular_componentnucleus
60003723molecular_functionRNA binding
60005515molecular_functionprotein binding
60016020cellular_componentmembrane
60019058biological_processviral life cycle
60020002cellular_componenthost cell plasma membrane
60030430cellular_componenthost cell cytoplasm
60044423cellular_componentvirion component
70006511biological_processubiquitin-dependent protein catabolic process
70031625molecular_functionubiquitin protein ligase binding
80006368biological_processtranscription elongation by RNA polymerase II
80030891cellular_componentVCB complex
80070449cellular_componentelongin complex
90006511biological_processubiquitin-dependent protein catabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
2SER34
7SER34
1CYS133
1HIS139
6HIS108
6CYS114
6CYS133
6HIS139

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648
ChainResidueDetails
2THR210
7THR210

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081
ChainResidueDetails
1THR96
6THR96

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine; by host => ECO:0000255|HAMAP-Rule:MF_04081
ChainResidueDetails
1SER145
6SER145

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081
ChainResidueDetails
1SER166
6SER166

223166

PDB entries from 2024-07-31

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