8FUP

Bromodomain of CBP liganded with BMS-536924 and CCS-1477

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CREB-binding protein	polymer	116	13847.9	2	UniProt (Q92793) Pfam (PF00439) In PDB	Homo sapiens (human)	Histone lysine acetyltransferase CREBBP,Protein-lysine acetyltransferase CREBBP
2	A	(3M)-4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[4-methyl-6-(morpholin-4-yl)-1H-benzimidazol-2-yl]pyridin-2(1H)-one	non-polymer		480.0	1	Chemie (N6I)
3	A, B	(6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one	non-polymer		534.6	2	Chemie (JHL)
4	A, B	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
5		water	water		18.0	304	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27695.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1797.4
All*	Total formula weight	29493.2

*Water molecules are not included.