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8FQE

LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DGlutamate receptor 2polymer88398854.94UniProt (P19491)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Rattus norvegicus (Norway rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2A, B, C, DGLUTAMIC ACIDnon-polymer147.14Chemie (GLU)
3A, B, C, DCYCLOTHIAZIDEnon-polymer389.94Chemie (CYZ)
4waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight395419.4
Non-Polymers*Number of molecules8
Total formula weight2148.0
All*Total formula weight397567.4
*Water molecules are not included.

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PDB entries from 2024-07-10

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