8FN8

Crystal structure of the C-terminal Fg domain of TNC with the single FN domain of PTPRZ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tenascin	polymer	231	26383.3	1	UniProt (P24821) Pfam (PF00147) In PDB	Homo sapiens (human)	TN,Cytotactin,GMEM,GP 150-225,Glioma-associated-extracellular matrix antigen,Hexabrachion,JI,Myotendinous antigen,Neuronectin,Tenascin-C,TN-C
2	B	Receptor-type tyrosine-protein phosphatase zeta	polymer	106	11914.3	1	UniProt (P23471) Pfam (PF00041) In PDB	Homo sapiens (human)	R-PTP-zeta,Protein-tyrosine phosphatase receptor type Z polypeptide 1,Protein-tyrosine phosphatase receptor type Z polypeptide 2,R-PTP-zeta-2
3	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
4		water	water		18.0	229	Chemie (HOH)

Sequence modifications

A: 1975 - 2201 (UniProt: P24821)

PDB	External Database	Details
Gly 1971	-	expression tag
Pro 1972	-	expression tag
Gly 1973	-	expression tag
Ser 1974	-	expression tag

B: 310 - 411 (UniProt: P23471)

PDB	External Database	Details
Gly 306	-	expression tag
Pro 307	-	expression tag
Gly 308	-	expression tag
Ser 309	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38297.6
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	38337.7

*Water molecules are not included.