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8FN3

Crystal structure of human DNA polymerase eta incorporating dITP across dC

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA templatepolymer123542.31Homo sapiens
3C
(P)
DNA primerpolymer82506.71Homo sapiens
4D
(A)
2'-deoxyinosine 5'-triphosphatenon-polymer492.21Chemie (Y43)
5E, F
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
6G, H, I
(A, T, P)
waterwater18.088Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54374.4
Non-Polymers*Number of molecules3
Total formula weight572.3
All*Total formula weight54946.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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