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8FMI

Crystal structure of human KRAS at 1.12 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 2B of GTPase KRaspolymer17019312.71UniProt (P01116-2)
Pfam (PF00071)
UniProt (by SIFTS) (P01116)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D
(A)
waterwater18.0278Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116-2)
PDBExternal DatabaseDetails
Gly 0-expression tag
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19312.7
Non-Polymers*Number of molecules2
Total formula weight467.5
All*Total formula weight19780.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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